Article

Comprehensive analysis of disease pathology in immunocompetent and immunocompromised hamster models of SARS-CoV-2 infection

2022-01-08

Abstract excerpt

<h4>ABSTRACT</h4> The pathogenesis of SARS-CoV-2 in the context of a specific immunological niche is not fully understood. Here, we used a golden Syrian hamster model to systematically evaluate the kinetics of host response to SARS-CoV-2 infection, following disease pathology, viral loads, antibody responses, and inflammatory cytokine expression in multiple organs. The kinetics of SARS-CoV-2 pathogenesis and geno...

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Literature Corpus work: a939d2bb-20ae-57cf-9ad5-87a0ee6c49bb
DOI: 10.1101/2022.01.07.475406

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