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Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis

2020-06-15

Abstract excerpt

<title>Abstract</title> <p>Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Cigarette smoke is a major etiological risk factor that has been shown to alter cellular processes involving mitochondrial function, cellular senescence and telomeric length. Here we determined how aging contribute to the alteration in the gene exp...

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Literature Corpus work: 90ee4f03-449c-5e2c-8b89-a506bbb312d7
DOI: 10.21203/rs.3.rs-35347/v1

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