Article

MKL1 Regulates Hepatocellular Carcinoma Cell Proliferation, Migration and Apoptosis via the COMPASS Complex and NF-Κb Signaling

2021-04-05

Abstract excerpt

<h4>Background: </h4> Histone modification plays essential roles in hepatocellular carcinoma (HCC) pathogenesis, but the regulatory mechanisms remain poorly understood. In this study, we aimed to analyze the roles of Megakaryoblastic leukemia 1 (MKL1) and its regulation of COMPASS (complex of proteins associated with Set1) in HCC cells. Methods MKL1 expression in clinical tissues and cell lines were detected by b...

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Literature Corpus work: 19dc20f6-da8b-503f-82b9-e7df68101518
DOI: 10.21203/rs.3.rs-390556/v1

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