Article

Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters

2024-07-17

Abstract excerpt

<h4>ABSTRACT</h4> The significant advances in the differentiation of human pluripotent stem (hPS) cells into pancreatic endocrine cells, including functional β-cells, have been based on a detailed understanding of the underlying developmental mechanisms. However, the final differentiation steps, leading from endocrine progenitors to mono-hormonal and mature pancreatic endocrine cells, remain to be fully understoo...

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Literature Corpus work: b528d731-96b2-5030-b557-2ddb5cdba499
DOI: 10.1101/2024.07.15.603551

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