Article

Noninvasive lung cancer detection via pulmonary protease profiling

2018-12-13

Abstract excerpt

Lung cancer is the leading cause of cancer-related death and patients most commonly present with incurable metastatic disease. National guidelines recommend screening for high-risk patients with low-dose computed tomography (LDCT), but this approach has limitations including high false positive rates. Activity-based nanosensors (ABNs) detect dysregulated proteases in vivo and release a reporter to provide a urina...

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Literature Corpus work: b5102485-44f8-58b4-b54b-278acddfca0d
DOI: 10.1101/495259

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