Article

Engineered Lactiplantibacillus plantarum as a Biosensor Probe for the Lungs

2023-09-27

Abstract excerpt

Lungs are a frequent site for disease but are difficult to image and probe, potentially exacerbating lung disease, delaying diagnoses and impacting survival. Here, we demonstrate a low cost, minimally invasive method to probe the lungs for disease, using genetically engineered Lactiplantibacillus plantarum strain WCFS1. Genetically modified WCFS1 was delivered specifically to the lungs of mice, where it was shown...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 19ddc6b5-23c4-58a2-bcb1-7d4d52522b42
DOI: 10.1101/2023.09.27.559779

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Engineered Lactiplantibacillus plantarum as a Biosensor Probe for the LungsDOI 10.1101/2023.09.27.559779Read

Noninvasive lung cancer detection via pulmonary protease profilingSemantic proximity Read

Bioluminescence Imaging Study of Spatial and Temporal Persistence of Lactobacillus plantarum and Lactococcus lactis in Living MiceSemantic proximity Read

<i>Lactococcus lactis</i>as a live vector for mucosal delivery of therapeutic proteinsSemantic proximity Read

The murine lung microbiome is dynamic and transientSemantic proximity Read

In vivo bioluminescence imaging of natural bacteria via ATP-binding cassette sugar transporterSemantic proximity Read

Programmable genetic control of tumor-colonizing Bifidobacterium longum for intratumoral therapeutic delivery and biocontainmentSemantic proximity Read

Genetically engineered bacterium: Principles, practices, and prospectsSemantic proximity Read

Let there be bioluminescence: development of a biophotonic imaging platform for in situ analyses of oral biofilms in animal modelsSemantic proximity Read

Lactococcus lactis as a Cell Factory for Delivery of Therapeutic ProteinsSemantic proximity Read

Genetically-programmed Hypervesiculation of <i>Lactiplantibacillus plantarum</i> Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease ModelSemantic proximity Read

Engineered bacteria detect tumor DNASemantic proximity Read

Implementation of Probiotic Bacteria for Monitoring Intestinal InflammationSemantic proximity Read