Article

Mitochondrial ATP-Sensitive K <sup>+</sup> Channels (MitoK <sub>ATP</sub> ) Regulate Brown Adipocyte Differentiation and Metabolism

2025-01-24

Abstract excerpt

Brown adipose tissue (BAT) plays a central role in mammalian non-shivering thermogenesis, dissipating mitochondrial membrane potentials through the activity of uncoupling protein UCP1 to release heat. Inner membranes of mitochondria are known to be permeable to potassium ions (K + ), which enter the matrix either through ATP-sensitive channels (MitoKATP) or leakage across the bilayer driven by inner membrane pote...

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Literature Corpus work: b50c024a-421d-52d8-ae23-4ea64f576c28
DOI: 10.1101/2025.01.21.634060

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