Article

AQP1- A regulatory factor associated with brown adipose tissue-silencing

2024-09-25

Abstract excerpt

The activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) by environmental cold challenge yields strong metabolic benefit in the face of diet-induced obesity (DIO). Yet, a critical barrier to leveraging brown fat NST for therapeutic use against metabolic disease is that BAT is silenced and inactive at physiological ambient temperature conditions in humans. The mechanisms that govern this si...

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Literature Corpus work: f24799c3-4a0c-51a2-b971-15a5b5b1dcb7
DOI: 10.1101/2024.09.23.614599

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