Article

Extracting Parsimonious Quantitative Predictors of Biological Effectiveness from ‘First-Principles’ Radiobiology: Application to the Mixed-Quality Problem

2026-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Developing parsimonious, mechanism-aware quantitative models that predict how biological effectiveness changes with different modifiers remains, in general, an unsolved problem. Advances in radiobiological research have created a large knowledge base of ‘first-principles’ mechanistic models of radiation response that, in principle, could accurately predict radiosensitivity across different exper...

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Literature Corpus work: b5079ec3-0f71-5962-b66c-048fe771056c
DOI: 10.64898/2026.05.02.722446

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