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On the Observability and Structural Identifiability of Radiobiological Models and the Case for Latent-State Adaptive Control

2026-05-13

Abstract excerpt

Mechanistic models in radiobiology have proliferated across FLASH ultra-high dose-rate radiotherapy, spatially fractionated radiation therapy (SFRT), and stereotactic body radiotherapy (SBRT), yet the field has not converged on unified mechanistic explanations despite decades of model development. We propose that this proliferation partly reflects a structural property of the model-observation pairing itself: clin...

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Literature Corpus work
38f13bc3-abba-53eb-a07a-1db05dbf4a7f
DOI
10.20944/preprints202605.0822.v1
Open publication

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On the Observability and Structural Identifiability of Radiobiological Models and the Case for Latent-State Adaptive ControlDOI 10.20944/preprints202605.0822.v1
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