Article

Actin disassembly triggers CNS myelin compaction and wrapping

2026-05-15

Abstract excerpt

<h4>SUMMARY</h4> Compact myelin enables rapid and precise impulse conduction in the vertebrate nervous system. During CNS development, oligodendrocytes wrap spirally around axons while compacting membranes, yet how cytoskeletal remodeling is coupled to these events remains unclear. Actin disassembly is required for wrapping, but whether wrapping is driven by iterative actin-based protrusion or follows a transitio...

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Literature Corpus work: b4fde5d5-aecc-53f2-931c-78eca93d9310
DOI: 10.64898/2026.05.14.722739

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