Article
A fast and accurate method for detection of IBD shared haplotypes in genome-wide SNP data.
European journal of human genetics : EJHG - 1 May 2017
Bjelland Douglas W, Lingala Uday, Patel Piyush S, Jones Matt, Keller Matthew C
Abstract excerpt
Identical by descent (IBD) segments are used to understand a number of fundamental issues in genetics. IBD segments are typically detected using long stretches of identical alleles between haplotypes in phased, whole-genome SNP data. Phase or SNP call errors in genomic data can degrade accuracy of IBD detection and lead to false-positive/negative calls and to under/overextension of true IBD segments. Furthermore,...
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