Article

RESPIRATION DEFECTS LIMIT SERINE SYNTHESIS REQUIRED FOR LUNG CANCER GROWTH AND SURVIVAL

2024-06-02

Abstract excerpt

<h4>SUMMARY</h4> Mitochondrial function is important for both energetic and anabolic metabolism. Pathogenic mitochondrial DNA (mtDNA) mutations directly impact these functions, resulting in the detrimental consequences seen in human mitochondrial diseases. The role of pathogenic mtDNA mutations in human cancers is less clear; while pathogenic mtDNA mutations are observed in some cancer types, they are almost abse...

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Literature Corpus work: b4ac1dcd-c27f-5853-8484-ca6ed8eff8a6
DOI: 10.1101/2024.05.28.596339

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