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Mitochondrial SHMT2 is a crucial therapeutic target in dedifferentiated thyroid cancer

2022-08-02

Abstract excerpt

<title>Abstract</title> <p>The roles of the serine/glycine metabolic pathway (SGP) have recently been evident in certain types of tumor physiology; however, the pathological relevance of SGP in undifferentiated thyroid cancer remains unexplored. Herein, we employed a comparative transcriptome analysis of bulk RNA sequencing coupled with single-cell RNA sequencing, showing that the high expression of <italic>SHMT2...

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Literature Corpus work
dcf07b8b-5277-5f01-9f2c-ae5f3eccf53f
DOI
10.21203/rs.3.rs-1881482/v1
Open publication

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