Article

A Single-Cell Woodchuck Liver Atlas Identifies Healthy and Disease-related Cellular Programs Conserved in Human

2025-03-03

Abstract excerpt

<h4>Background</h4> Model organisms allowing for longitudinal examinations of liver disease pathogenesis are pivotal for the development of new therapeutic modalities. The eastern North American woodchuck develops chronic hepatitis and liver cancer after woodchuck hepatitis virus (WHV) infection, mirroring aspects of the natural history of the human hepatitis B virus (HBV). However, the cellular landscape of the...

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Literature Corpus work: b4ac0835-f4ef-5b63-bfba-c60767f5ae42
DOI: 10.1101/2025.03.03.641192

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