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Article

Transcriptomic analysis of the woodchuck model of chronic hepatitis B

20 Mar 2012

Abstract excerpt

UNLABELLED: The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in humans, but the lack of sequence information has hitherto precluded functional genomics analysis. To...

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PMID: 22431061
DOI: 10.1002/hep.25730

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