Article

Discovery and Characterization of Interleukin-4-Specific Affibodies for Affinity-Controlled Protein Release and Macrophage Polarization

2026-05-12

Abstract excerpt

Interleukin-4 (IL-4) is a key immunoregulatory cytokine that promotes type 2 inflammation, drives macrophage polarization toward an anti-inflammatory M2 phenotype, and supports tissue repair. However, clinical translation of IL-4 therapies to modulate the immune response is limited by the need for precise control over its delivery to avoid immune dysregulation. Here, we report an affinity-based strategy to modulat...

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Literature Corpus work: b46ad772-4c0b-570e-bd07-c83298e4e12b
DOI: 10.64898/2026.05.07.723637

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Discovery and Characterization of Interleukin-4-Specific Affibodies for Affinity-Controlled Protein Release and Macrophage PolarizationDOI 10.64898/2026.05.07.723637Read

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