Article

Ciliary-Enriched and Keratinization-Dominant Endotypes Drive Molecular Heterogeneity in AECOPD

2026-04-20

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Acute exacerbations of COPD (AECOPD) involve poorly characterized airway host responses. Integrating sputum proteomics with radiomics may reveal underlying molecular heterogeneity and identify clinically relevant biomarkers. <bold>Methods:</bold> We performed deep proteomic profiling on induced sputum from patients with AECOPD (n=35), stable COPD (n=19), an...

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Literature Corpus work: b4454167-a632-56b1-9467-f03ffaf3efbd
DOI: 10.21203/rs.3.rs-9347057/v1

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