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Article

Identification of Mucus-Associated Molecular Subtypes of Chronic Obstructive Pulmonary Disease: A Latent Profile Analysis Based on MUC5B-Associated Genes.

Medical science monitor : international medical journal of experimental and clinical research - 14 Aug 2021

Hu Yuanlong, Cheng Xiaomeng, Qiu Zhanjun, Chen Xianhai

Abstract excerpt

BACKGROUND Chronic obstructive pulmonary disease (COPD) is a disease with high heterogeneity, which is a major challenge in clinical individualized treatment. A mucus phenotype is one of the main characteristics of COPD. MATERIAL AND METHODS Gene expression profiles of lung tissue samples were from the Lung Genomics Research Consortium. MUC5B-associated gene signatures were obtained based on a nonlinear feature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34389698
DOI: 10.12659/MSM.931222
PMCID: PMC8372096

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