Article

All protein aggregates will thermodynamically order

2020-09-16

Abstract excerpt

Proteins can aggregate into disordered liquid droplets or ordered assemblies such as amyloid fibrils. These two distinct phases determine the spatial organization within cells and serve differing roles in a wide range of biological functions including gene regulation, organelle and synapse formation, and memory consolidation. The ordered phase can also give rise to diseases such as Alzheimer’s. However, how the pr...

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Literature Corpus work: b40c5d6b-f307-517d-b628-b2cacb153ac5
DOI: 10.1101/2020.09.15.278408

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