Article

Genome-wide association study identifies a new susceptibility locus in <i>PLA2G4C</i> for Multiple System Atrophy

2023-05-03

Abstract excerpt

To elucidate the molecular basis of multiple system atrophy (MSA), a neurodegenerative disease, we conducted a genome-wide association study (GWAS) in a Japanese MSA case/control series followed by replication studies in Japanese, Korean, Chinese, European and North American samples. In the GWAS stage rs2303744 on chromosome 19 showed a suggestive association ( P = 6.5 × 10 −7 ) that was replicated in additional...

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Literature Corpus work: b3df8909-b257-5318-8117-ea1188b59806
DOI: 10.1101/2023.05.02.23289328

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