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Article

Cross-examining candidate genes implicated in multiple system atrophy

24 Jul 2019

Abstract excerpt

Multiple system atrophy (MSA) is a devastating neurodegenerative disease characterized by the clinical triad of parkinsonism, cerebellar ataxia and autonomic failure, impacting on striatonigral, olivopontocerebellar and autonomic systems. At early stage of the disease, the clinical symptoms of MSA can overlap with those of Parkinson's disease (PD). The key pathological hallmark of MSA is the presence of glial...

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PMID: 31340844
DOI: 10.1186/s40478-019-0769-4

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