Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetic basis of multiple system atrophy

10 Feb 2023

Abstract excerpt

Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism, cerebellar dysfunction, and corticospinal degeneration. The underlying pathophysiology is postulated to arise from aberrant ɑ-synuclein deposition, mitochondrial dysfunction, oxidative stress and neuroinflammation. Although MSA is regarded as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neurological diseases and metabolism
Share to Nuclear Receptors and Signaling
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36765380
DOI: 10.1186/s12967-023-03905-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic basis of multiple system atrophyPMID 36765380Read ↗

Genetic players in multiple system atrophy: unfolding the nature of the beast.Semantic proximity Read ↗

Multiple System Atrophy: Genetic or Epigenetic?Semantic proximity Read ↗

Multiple system atrophy: the application of genetics in understanding etiology.Semantic proximity Read ↗

Multiple System Atrophy: Pathology, Pathogenesis, and Path ForwardSemantic proximity Read ↗

Multiple system atrophy: genetic risks and alpha-synuclein mutationsSemantic proximity Read ↗

Cross-examining candidate genes implicated in multiple system atrophySemantic proximity Read ↗

Genome sequence analyses identify novel risk loci for multiple system atrophy.Semantic proximity Read ↗

Genome-wide estimate of the heritability of Multiple System Atrophy.Semantic proximity Read ↗

Heterogeneity of Multiple System Atrophy: An UpdateSemantic proximity Read ↗

Associations between multiple system atrophy and polymorphisms of SLC1A4, SQSTM1, and EIF4EBP1 genes.Semantic proximity Read ↗

Pathology and genetics of multiple system atrophy: an approach to determining genetic susceptibility spectrum.Semantic proximity Read ↗

Understanding the pathogenesis of multiple system atrophy: state of the art and future perspectivesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.