Article
Associations between multiple system atrophy and polymorphisms of SLC1A4, SQSTM1, and EIF4EBP1 genes.
Movement disorders : official journal of the Movement Disorder Society - 15 Jun 2008
Soma Hiroyuki, Yabe Ichiro, Takei Asako, Fujiki Naoto, Yanagihara Tetsuro, Sasaki Hidenao
Abstract excerpt
Multiple system atrophy (MSA) is an adult-onset sporadic neurodegenerative disease. Although the etiology of MSA remains obscure, recent studies suggest that oxidative stress is associated with the pathogenesis of MSA. The aim of this study was to evaluate genetic associations between the candidate genes involved in oxidative stress and MSA in a case-control study. We examined 119 Japanese patients with MSA and...
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