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Genome-wide association study of autopsy-confirmed Multiple System Atrophy identifies common variants near <i>ZIC1</i> and <i>ZIC4</i>

2021-11-12

Abstract excerpt

Multiple System Atrophy is a rare neurodegenerative disease with alpha-synuclein aggregation in glial cytoplasmic inclusions and either predominant olivopontocerebellar atrophy or striatonigral degeneration, leading to dysautonomia, parkinsonism, and cerebellar ataxia. One prior genome-wide association study in mainly clinically diagnosed patients with Multiple System Atrophy failed to identify genetic variants pr...

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Literature Corpus work
408c80eb-a8f8-534a-a38d-98c6727e8483
DOI
10.1101/2021.11.11.21265915
Open publication

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Genome-wide association study of autopsy-confirmed Multiple System Atrophy identifies common variants near <i>ZIC1</i> and <i>ZIC4</i>DOI 10.1101/2021.11.11.21265915
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