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Article

Genetic players in multiple system atrophy: unfolding the nature of the beast.

Neurobiology of aging - 1 Oct 2011

Stemberger Sylvia, Scholz Sonja W, Singleton Andrew B, Wenning Gregor K

Abstract excerpt

Multiple system atrophy (MSA) is a fatal oligodendrogliopathy characterized by prominent α-synuclein inclusions resulting in a neuronal multisystem degeneration. Until recently MSA was widely conceived as a nongenetic disorder. However, during the last years a few postmortem verified Mendelian pedigrees have been reported consistent with monogenic disease in rare cases of MSA. Further, within the last 2 decades...

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Identifiers

PMID: 21601954
DOI: 10.1016/j.neurobiolaging.2011.04.001
PMCID: PMC3157605

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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