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Drospondin, a novel glial-secreted glycoprotein, controls the development and function of the <i>Drosophila</i> nervous system

2024-11-09

Abstract excerpt

<h4>ABSTRACT</h4> Reelin is a secreted glycoprotein with roles in the development of the mammalian neocortex, hippocampus and cerebellum. This vertebrate signaling molecule also contributes to adult brain function. Mammalian Reelin increases the complexity of Drosophila Mushroom Body (MB) neurites, an effect mediated by LpR1 and LpR2, the orthologs of mammalian Reelin receptors. Paradoxically, to date, no Reelin...

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Literature Corpus work
b3ce5dab-99b6-5aec-a288-fdd46a56a579
DOI
10.1101/2024.11.08.622737
Open publication

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Drospondin, a novel glial-secreted glycoprotein, controls the development and function of the <i>Drosophila</i> nervous systemDOI 10.1101/2024.11.08.622737
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