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AdhE spirosome length in enterohaemorrhagic <i>Escherichia coli</i> is correlated with enzymatic directionality and is perturbed by salicylidene acylhydrazide binding

2024-01-29

Abstract excerpt

<h4>ABSTRACT</h4> Antibiotics are contraindicated for the treatment of infection enterohemorrhagic Escherichia coli (EHEC), a human pathogen that causes diarrhea or hemorrhagic colitis in humans which can progress to hemolytic uremic syndrome (HUS). As an alternative to the use of antibiotics, previous studies developed the salicylidene acylhydrazides (SA), a family of anti-virulence compounds capable of blockin...

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Literature Corpus work
b3ca42bf-d1c4-59c1-9a50-809b98cba678
DOI
10.1101/2024.01.25.577206
Open publication

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AdhE spirosome length in enterohaemorrhagic <i>Escherichia coli</i> is correlated with enzymatic directionality and is perturbed by salicylidene acylhydrazide bindingDOI 10.1101/2024.01.25.577206
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