Article

Structural control for the coordinated assembly into functional pathogenic type-3 secretion systems

2019-07-24

Abstract excerpt

Functional injectisomes of the type-3 secretion system assemble into highly defined and stoichiometric bacterial molecular machines essential for infecting human and other eukaryotic cells. However, the mechanism that governs the regulated step-wise assembly process from the nucleation-phase, to ring-assembly, and the filamentous phase into a membrane embedded needle complex is unclear. We here report that the for...

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Literature Corpus work: 97e7d8c7-a2ed-532b-83e3-86a3fe14b801
DOI: 10.1101/714097

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