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Article

Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli.

PLoS pathogens - 1 Sept 2014

Berry Andrea A, Yang Yi, Pakharukova Natalia, Garnett James A, Lee Wei-chao, Cota Ernesto, Marchant Jan, Roy Saumendra, Tuittila Minna, Liu Bing, Inman Keith G, Ruiz-Perez Fernando, Mandomando Inacio, Nataro James P, Zavialov Anton V, Matthews Steve

Abstract excerpt

Enteroaggregative Escherichia coli (EAEC) is a leading cause of acute and persistent diarrhea worldwide. A recently emerged Shiga-toxin-producing strain of EAEC resulted in significant mortality and morbidity due to progressive development of hemolytic-uremic syndrome. The attachment of EAEC to the human intestinal mucosa is mediated by aggregative adherence fimbria (AAF). Using X-ray crystallography and NMR...

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Share to Adhesins, Escherichia coli
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Escherichia coli Infections

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Share to Fimbriae, Bacterial

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Source

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Identifiers

PMID: 25232738
DOI: 10.1371/journal.ppat.1004404
PMCID: PMC4169507

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SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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