Article
Endometrial polyps are non-neoplastic but harbor epithelial mutations in endometrial cancer drivers at low allelic frequencies.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2022
Sahoo Subhransu S, Aguilar Mitzi, Xu Yan, Lucas Elena, Miller Valerie, Chen Hao, Zheng Wenxin, Cuevas Ileana C, Li Hao-Dong, Hitrys David, Wachsmann Megan B, Bishop Justin A, Cantarell Brandi, Gagan Jeffrey, Koduru Prasad, SoRelle Jeffrey A, Castrillon Diego H
Abstract excerpt
Endometrial polyps (EMPs) are common exophytic masses associated with abnormal uterine bleeding and infertility. Unlike normal endometrium, which is cyclically shed, EMPs persist over ovulatory cycles and after the menopause. Despite their usual classification as benign entities, EMPs are paradoxically associated with endometrial carcinomas of diverse histologic subtypes, which frequently arise within EMPs. The...
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