Article

Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1

2017-12-11

Abstract excerpt

<h4>Background: </h4> The human leukaemia virus HTLV-1 expresses essential accessory genes that manipulate the expression, splicing and transport of viral mRNAs. Two of these genes, tax and hbz , also promote proliferation of the infected cell, and both genes are thought to contribute to oncogenesis in adult T-cell leukaemia/lymphoma. The regulation of HTLV-1 proviral latency is not understood. tax, on the pro...

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Literature Corpus work: b3992877-61bd-5118-9329-3549787b41ad
DOI: 10.12688/wellcomeopenres.12469.2

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