Article

Quantification of HTLV-1 expression at the single-cell level in naturally-infected T-lymphocytes

2018-01-01

Abstract excerpt

The human leukaemia virus HTLV-1 expresses essential accessory genes that manipulate the expression, splicing and transport of viral mRNAs. Two of these genes, tax and hbz, also promote proliferation of the infected cell, and both genes are thought to contribute to oncogenesis in adult T-cell leukaemia/lymphoma. The regulation of HTLV-1 proviral latency is not understood. tax, on the proviral plus strand, is usual...

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Literature Corpus work: 6e8524b3-9862-5681-a2b9-6e5fde270a1c
DOI: 10.25560/59040

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