Article

The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle

2023-01-08

Abstract excerpt

Infections by Human T cell Leukaemia Virus type 1 (HTLV-1) persist for the lifetime of the host by integrating into the genome of CD4 + T cells. Proviral gene expression is core to proviral survival and the maintenance of the proviral load, through the pro-proliferative changes it induces in infected cells. Despite their role in HTLV-1 infection and a persistent cytotoxic T lymphocyte response raised against them...

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Literature Corpus work: 84a09bf3-71b1-587d-b7b6-3c5dfdc4c51a
DOI: 10.1101/2023.01.08.523159

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