Article

The immunochemical characterisation, epitope analysis and diagnostic applications of neo-antigens formed by lipoxidation of human serum albumin

2020-01-01

Abstract excerpt

Lipid oxidation has long been linked to the generation of toxic products seen to trigger many different anti-inflammatory responses. Products such as 4-hydroxynonenal (HNE) and acrolein can react with nucleophilic groups in proteins to form lipoxidation adducts, that have been detected in diseases like diabetes, cancer and cardiovascular diseases and, hence, are considered powerful biomarkers of oxidative stress i...

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Literature Corpus work: b3912677-941e-5217-a571-e07b7990cf42
DOI: 10.48780/publications.aston.ac.uk.00042533

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