Article
Biological functions of haptoglobin--new pieces to an old puzzle.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies - 1 Sept 1997
Dobryszycka W
Abstract excerpt
Haptoglobin, an "acute phase" protein, has different functions, which display genetic polymorphism. The complex of haptoglobin with haemoglobin is metabolized in the heptic reticuloendothelial system. Biosynthesis of haptoglobin occurs not only in the liver, but also in adipose tissue and in lung; providing antioxidant and antimicrobial activity. Changes in the measured concentrations of haptoglobin in serum may...
Topics
- Animals
- Gene Expression Regulation
- Haptoglobins
- Hemoglobins
- Humans
- Infections
- Inflammation
- Leukocytes
- Phenotype
- Protein Binding
