Article
Pharmaceutically important pre- and posttranslational modifications on human serum albumin.
Biological & pharmaceutical bulletin - 1 Apr 2009
Otagiri Masaki, Chuang Victor Tuan Giam
Abstract excerpt
Recombinant technology allows engineering and production of proteins with desirable properties. Human serum albumin has been developed with recombinant technology, and thus plays an increasing role as a drug carrier in the clinical setting. Genetic variations usually occur on the surface of the protein, and do not impose significant effects on the conformation of albumin. However, binding of fatty acids by...
Topics
- Genetic Variation
- Humans
- Models, Molecular
- Protein Processing, Post-Translational
- Serum Albumin
