Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Response of human macrophages to wound matrices in vitro.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1 May 2016

Witherel Claire E, Graney Pamela L, Freytes Donald O, Weingarten Michael S, Spiller Kara L

Abstract excerpt

Chronic wounds remain a major burden to the global healthcare system. Myriad wound matrices are commercially available but their mechanisms of action are poorly understood. Recent studies have shown that macrophages are highly influenced by their microenvironment, but it is not known how different biomaterials affect this interaction. Here, it was hypothesized that human macrophages respond differently to changes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biocompatible Materials
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cellular Microenvironment

Share to Macrophages

Share to Materials Testing

Share to Neovascularization, Physiologic

Share to Tissue Scaffolds

Share to Wound Healing

Source

Identifiers

PMID: 26874797
DOI: 10.1111/wrr.12423

Genes

CCL22
TIMP3
MRC1
NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Response of human macrophages to wound matrices in vitro.PMID 26874797Read ↗

An immunocompetent bioengineered human dermal equivalent to recapitulate scar tissue formation in vitroSemantic proximity Read ↗

Macrophage phenotypes in tissue repair and the foreign body response: Implications for biomaterial-based regenerative medicine strategies.Semantic proximity Read ↗

Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophagesSemantic proximity Read ↗

Collagenase-based wound debridement agent induces extracellular matrix supporting phenotype in macrophages.Semantic proximity Read ↗

Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophages.Semantic proximity Read ↗

Macrophage phenotype in response to ECM bioscaffolds.Semantic proximity Read ↗

Characterizing the Macrophage Response to Immunomodulatory Biomaterials Through Gene Set Analyses.Semantic proximity Read ↗

Artificial extracellular matrices composed of collagen I and high-sulfated hyaluronan promote phenotypic and functional modulation of human pro-inflammatory M1 macrophages.Semantic proximity Read ↗

Transcriptome-targeted analysis of human peripheral blood-derived macrophages when cultured on biomaterial meshes.Semantic proximity Read ↗

Engineering a reproducible 3D wound model with defined macrophage polarization and partial-thickness mechanical injurySemantic proximity Read ↗

Macrophage Phenotypes in Normal and Diabetic Wound Healing and Therapeutic Interventions.Semantic proximity Read ↗

Xenogeneic Skin Transplantation Promotes Angiogenesis and Tissue Regeneration Through Vitamin D-Activated Trem2+ MacrophagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.