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Pre-clinical testing of two serologically distinct chimpanzee-origin adenovirus vectors expressing spike of SARS-CoV-2

2023-09-29

Abstract excerpt

<title>Abstract</title><p>Two serologically distinct chimpanzee-origin, replication-defective adenovirus (AdC) vectors expressing the spike (S) protein of an early severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolate were generated and tested for induction of antibodies in mice. Both vectors induced S protein-specific antibodies including neutralizing antibodies. Levels of antibodies increased afte...

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Literature Corpus work
b37a9b8b-a3cb-5568-8a2b-4909382801f9
DOI
10.21203/rs.3.rs-3314638/v1
Open publication

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Pre-clinical testing of two serologically distinct chimpanzee-origin adenovirus vectors expressing spike of SARS-CoV-2DOI 10.21203/rs.3.rs-3314638/v1
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