Article

TREM2 affects DAM-like cell transformation in the acute phase of TBI in mice by regulating microglial glycolysis

2024-10-14

Abstract excerpt

<title>Abstract</title> <p>Background Traumatic brain injury (TBI) is characterized by high mortality and disability rates. Disease-associated microglia (DAM) are a newly discovered subtype of microglia. However, their presence and function in the acute phase of TBI remain unclear. Although glycolysis is important for microglial differentiation, its regulatory role in DAM transformation during the acute phase of...

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Literature Corpus work: b3793339-c8c6-5034-9bf0-842eb52db95c
DOI: 10.21203/rs.3.rs-5238506/v1

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