Article

Three-dimensional tissue stiffness mapping in the mouse embryo supports durotaxis during early limb bud morphogenesis

2018-09-08

Abstract excerpt

<h4>ABSTRACT</h4> Numerous biophysical hypotheses invoke tissue stiffness as a key parameter for shaping tissue during development and for influencing cell behaviours during disease progression. However, currently available methods are insufficient to test hypotheses that concern the physical properties of bulk tissues. Here we introduce, validate and apply a new 3D magnetic device that generates a uniform magnet...

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Identifiers and source

Literature Corpus work: b35c46ea-34c9-51e8-aa53-2e297d9aae36
DOI: 10.1101/412072

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