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Engineering viral vectors for acoustically targeted gene delivery

10 Jun 2024

Abstract excerpt

Targeted gene delivery to the brain is a critical tool for neuroscience research and has significant potential to treat human disease. However, the site-specific delivery of common gene vectors such as adeno-associated viruses (AAVs) is typically performed via invasive injections, which limit its applicable scope of research and clinical applications. Alternatively, focused ultrasound blood-brain-barrier opening...

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PMID: 38858354
DOI: 10.1038/s41467-024-48974-y

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