Article

Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction

2014-09-15

Abstract excerpt

With the pace of scientific advancement accelerating rapidly, new methods are needed for experimental neuroscience to quickly and easily manipulate gene expression in the mouse brain. Here we describe a technique first introduced by Passini and Wolfe for direct intracranial delivery of virally-encoded transgenes into the neonatal mouse brain. In its most basic form, the procedure requires only an ice bucket and a...

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Identifiers and source

Literature Corpus work: ddc28249-e004-569e-9d2b-f799a687f3c7
DOI: 10.3791/51863-v

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