Article

Targeted protein evolution in the gut microbiome by diversity-generating retroelements

2024-11-16

Abstract excerpt

<h4>Summary</h4> Diversity-generating retroelements (DGRs) accelerate evolution by rapidly diversifying variable proteins. The human gastrointestinal microbiota harbors the greatest density of DGRs known in nature, suggesting they play adaptive roles in this environment. We identified >1,100 unique DGRs among human-associated Bacteroides species and discovered a subset that diversify adhesive components of Type...

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Literature Corpus work: a1106a5e-52e3-5cb3-b63d-13fe36a501a1
DOI: 10.1101/2024.11.15.621889

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