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Microglial ApoD Induced NLRC4 Inflammasome Activation Promotes Alzheimer’s Disease Progression

2021-06-14

Abstract excerpt

Alzheimer’s disease (AD) is a progressive neurodegenerative disease with no effective therapies. It’s well-known that chronic neuroinflammation plays a critical role in the onset and progression of AD. Proper neuronal-microglial interactions are essential for brain functions. However, as the main existence of immune cells, determining the role of microglia in Alzheimer’s neuroinflammation and the associated molecu...

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Literature Corpus work
bfc03913-f51d-523b-b76f-cf7eb2b15ddb
DOI
10.21203/rs.3.rs-558819/v1
Open publication

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