Article

Development of RNAseq methodologies to profile the <i>in vivo</i> transcriptome of <i>Bordetella pertussis</i> during murine lung infection

2017-05-22

Abstract excerpt

Bordetella pertussis is an obligate human respiratory pathogen that causes the disease whooping cough. A whole cell vaccine (DTP) was developed in the 1940s and was subsequently replaced in the 1990s with a protein-based subunit acellular vaccine (DTaP; tdap). Today, we are observing a resurgence of whooping cough due to evolution of the pathogen and waning vaccine immunity. The use of vaccines decreased the need...

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Literature Corpus work: b30ec929-949d-5f0b-858c-1a9bb24ef25c
DOI: 10.1101/140632

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