Back to search

Article

A highly conserved sRNA downregulates multiple genes, including a σ <sup>54</sup> transcriptional activator, in the virulence mode of <i>Bordetella pertussis</i>

2024-11-19

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial sRNAs together with the RNA chaperone Hfq post-transcriptionally regulate gene expression by affecting ribosome binding or mRNA stability. In the human pathogen Bordetella pertussis , the causative agent of whooping cough, hundreds of sRNAs have been identified, but their roles in B. pertussis biology are mostly unknown. Here we characterize a Hfq-dependent sRNA (S17), whose level is...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4367908e-2ca8-56ad-a133-2ef14e01a3bb
DOI
10.1101/2024.11.19.624354
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A highly conserved sRNA downregulates multiple genes, including a σ <sup>54</sup> transcriptional activator, in the virulence mode of <i>Bordetella pertussis</i>DOI 10.1101/2024.11.19.624354
RNase III and RNase E Influence Posttranscriptional Regulatory Networks Involved in Virulence Factor Production, Metabolism, and Regulatory RNA Processing in Bordetella pertussis.Semantic proximity
The Intergenic Small Non-Coding RNA <i>ittA</i> is Required for Optimal Infectivity and Tissue Tropism in <i>Borrelia burgdorferi</i>Semantic proximity
The small non-coding RNA B11 regulates multiple facets of <i>Mycobacterium abscessus</i> virulenceSemantic proximity
Extensive diversity in RNA termination and regulation revealed by transcriptome mapping for the Lyme pathogen <i>B. burgdorferi</i>Semantic proximity
Deep genome annotation of the opportunistic human pathogen <i>Streptococcus pneumoniae</i> D39Semantic proximity
Detection of small RNAs in Bordetella pertussis and identification of a novel repeated genetic element.Semantic proximity
DNA uptake and twitching motility are controlled by the small RNA Arp through repression of pilin translation in <i>Acinetobacter baumannii</i>Semantic proximity
The BvgAS Regulon of Bordetella pertussisSemantic proximity
An lp17-encoded small non-coding RNA with a potential regulatory role in mammalian host adaptation by the Lyme disease spirocheteSemantic proximity
<i>Coxiella burnetii</i> small RNA 12 binds CsrA regulatory protein and transcripts for the CvpD type IV effector, regulates pyrimidine and methionine metabolism, and is necessary for optimal intracellular growth and vacuole formation during infectionSemantic proximity
Novel small RNAs expressed by <i>Bartonella bacilliformis</i> under multiple conditions reveal potential mechanisms for persistence in the sand fly vector and human hostSemantic proximity
Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment.Semantic proximity
Select a neighboring publication to make it the new centre.