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Article

Proteomic Adaptation of Australian Epidemic Bordetella pertussis.

Proteomics - 1 Apr 2018

Luu Laurence Don Wai, Octavia Sophie, Zhong Ling, Raftery Mark J, Sintchenko Vitali, Lan Ruiting

Abstract excerpt

Bordetella pertussis causes whooping cough. The predominant strains in Australia changed to single nucleotide polymorphism (SNP) cluster I (pertussis toxin promoter allele ptxP3/pertactin gene allele prn2) from cluster II (non-ptxP3/non-prn2). Cluster I was mostly responsible for the 2008-2012 Australian epidemic and was found to have higher fitness compared to cluster II using an in vivo mouse competition assay,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29464899
DOI: 10.1002/pmic.201700237

Genes

TLR2

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