Article

POGZ suppresses 2C transcriptional program and retrotransposable elements

2022-11-03

Abstract excerpt

<h4>ABSTRACT</h4> The POGZ gene has been found frequently mutated in neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and intellectual disability (ID). We have recently shown that POGZ maintains mouse embryonic stem cells (ESCs) as a chromatin regulator and a transcription factor. However, the exact mechanisms remain unclear. Here we show that POGZ plays important role in the maintenanc...

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Literature Corpus work: b2da1865-8214-5cef-a5de-77dfb31ab1c0
DOI: 10.1101/2022.11.02.514968

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