Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis.

PLoS medicine - 1 Feb 2006

Badellino Karen O, Wolfe Megan L, Reilly Muredach P, Rader Daniel J

Abstract excerpt

BACKGROUND: Endothelial lipase (EL), a new member of the lipase family, has been shown to modulate high-density lipoprotein (HDL-C) metabolism and atherosclerosis in mouse models. We hypothesized that EL concentrations would be associated with decreased HDL-C and increased atherosclerosis in humans. METHODS AND FINDINGS: Healthy individuals with a family history of premature coronary heart disease (n = 858) were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticoagulants
Share to Cholesterol, HDL
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heparin

Share to Lipase

Share to Metabolic Syndrome

Share to Overweight

Share to Specimen Handling

Source

Open in PubMed Open full text

Identifiers

PMID: 16354105
DOI: 10.1371/journal.pmed.0030022
PMCID: PMC1316064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis.PMID 16354105Read ↗

Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism.Semantic proximity Read ↗

Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis.Semantic proximity Read ↗

Endothelial lipase is a major determinant of HDL level.Semantic proximity Read ↗

Endothelial lipase is a major determinant of HDL levelSemantic proximity Read ↗

Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice.Semantic proximity Read ↗

Hepatic lipase, high density lipoproteins, and hypertriglyceridemia.Semantic proximity Read ↗

LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization studySemantic proximity Read ↗

Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans.Semantic proximity Read ↗

Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol.Semantic proximity Read ↗

Hepatic lipase: a marker for cardiovascular disease risk and response to therapy.Semantic proximity Read ↗

Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender, and diet.Semantic proximity Read ↗

Genetic and structure-function studies of missense mutations in human endothelial lipase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.